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41.
Maya Vetencourt JF Sale A Viegi A Baroncelli L De Pasquale R O'Leary OF Castrén E Maffei L 《Science (New York, N.Y.)》2008,320(5874):385-388
We investigated whether fluoxetine, a widely prescribed medication for treatment of depression, restores neuronal plasticity in the adult visual system of the rat. We found that chronic administration of fluoxetine reinstates ocular dominance plasticity in adulthood and promotes the recovery of visual functions in adult amblyopic animals, as tested electrophysiologically and behaviorally. These effects were accompanied by reduced intracortical inhibition and increased expression of brain-derived neurotrophic factor in the visual cortex. Cortical administration of diazepam prevented the effects induced by fluoxetine, indicating that the reduction of intracortical inhibition promotes visual cortical plasticity in the adult. Our results suggest a potential clinical application for fluoxetine in amblyopia as well as new mechanisms for the therapeutic effects of antidepressants and for the pathophysiology of mood disorders. 相似文献
42.
Merja Veteläinen Eero Nissilä P. M. A. Tigerstedt Roland von Bothmer 《Euphytica》1996,92(1-2):267-273
Summary Utilization of exotic germplasm is one way to broaden genetic variation in breeding populations. This approach has recently been adopted in Sweden and Finland, where experimental barley populations has been established for research and pre-breeding purposes. The aim of the project is threefold: (1) to increase overall genetic diversity of Nordic barley breeding material; (2) to develop breeding material which possesses a high level of resistance for various barley diseases; and (3) to study effects of exotic germplasm on adaptation and agronomic performance. Both the Finnish and the Swedish barley populations include the same exotic material i.e. unadapted landraces from different parts of Asia and wild barley (Hordeum vulgare ssp. spontaneum) accessions. Locally adapted high-yielding barley lines were included in the populations. The establishment of these populations involved six crossing generations in order to promote recombination and enhance the break-up of linkage blocks. The paper discusses the third aim of the project. Studies on agronomic performance and adaptation showed that (1) agronomically valuable genotypes can be constructed through recombination using exotic germplasm for Nordic conditions, (2) that incorporation of exotic material is most successful when made in a local genetic base and (3) that exotic germplasm has an effect on adaptation. 相似文献
43.
Eero Varis Leena Pietilä Kauko Koikkalainen 《Acta Agriculturae Scandinavica, Section B - Plant Soil Science》2013,63(1):41-48
Abstract In 1987, a potato research project called “Minimized use of chemical inputs in potato production” was started in all five Scandinavian countries. In this paper, the results of one field trial series carried out at the Potato Research Institute, Lammi, Finland, during the years 1987–90 are reported. The main plots in a split-plot designed trial series consisted of three cropping systems: conventional, integrated and organic. The subplots included three cultivars differing especially in their late blight (Phythophtora infestans, (Mont.) de Bary) resistance: Bintje, Record and Matilda. Canopy measurements showed differences that can be attributed to different nitrogen supply in decreasing order from conventional to integrated to organic system. The trial sites were very heavily infested with potato scab, resulting in a very low percentage of I-class yield in susceptible cultivars Bintje and Matilda. Late blight was a serious problem in organically grown Bintje, as expected. Total yields in the integrated and organic systems were 10% and 36% lower, respectively, than in the conventional system. There was an interaction between cropping system and cultivar in favour of Bintje and the conventional system and Record in the organic system. The percentage of I-class yield was lowest in the conventional system. Some of the quality characteristics were slightly improved in the integrated and/or organic systems. Storage losses, caused mainly by tuber blight, were high in organically grown potatoes. There were no large differences in production costs between the cropping systems. The main determinants of the unit production cost of potatoes were total yield and yield of I-class potatoes. The average unit costs were 1.76 FIM kg?1 in the conventional, 1.68 FIM kg?1 in the integrated and 2.36 FIM kg?1 in the organic system. Record showed the lowest unit production costs in all systems ?1.33, 1.37 and 1.80 FIM kg?1, respectively. 相似文献
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46.
Eero Jutila Erkki Jokikokko Irma Kallio-Nyberg Irma Saloniemi Pentti Pasanen 《Fisheries Research》2003,60(2-3):333-343
The effect of origin, smolt size and year of release on the sea migration pattern of Atlantic salmon (Salmo salar L.) in the Baltic Sea was examined by tagging experiments conducted in 1991–1993 on wild and reared smolts of the Simojoki river salmon stock. The tag recovery data analysed by log-linear models revealed significant differences in both spatial and temporal sea migrations between the wild and reared salmon; the variation was attributed to the year of release and to the origin of the fish. Grilse accounted for the majority of reared returners (76%) but for a smaller proportion (46%) of the wild fish. The effect of smolt size could be studied only in the smolt groups tagged in 1991. Wild fish were more frequently (71%) caught in the Baltic Main Basin than were reared fish (51%) during their second sea year, and the size variation between wild and reared smolts did not explain the recovery site. No such differences in spatial distribution were found during the third sea year. The tagging place (hatchery/trap) of the reared fish did not affect their later sea migration. The differences in sea migration patterns suggest that the wild salmon are more vulnerable to the intensive salmon fishery in the Baltic Main Basin than are reared fish. 相似文献
47.
Anna Valros Camilla Munsterhjelm Eero Puolanne Marita Ruusunen Mari Heinonen Olli A T Peltoniemi A Reeta P?s? 《Acta veterinaria Scandinavica》2013,55(1):75
Background
Tail biting is a common welfare problem in pig production and in addition to being a sign of underlying welfare problems, tail biting reduces welfare in itself. The aim of this study was to evaluate the effects of tail biting on different pre and post mortem indicators of stress in slaughter pigs and on carcass and meat characteristics. A total of 12 tail bitten (TB) and 13 control (C) pigs from a farm with a long-term tail biting problem were selected for salivary cortisol analyses before and after transport to the slaughterhouse. After stunning, samples were taken for the analysis of serum cortisol, blood lactate, intestinal heat shock protein 70 (HSP70), and meat quality characteristics. In addition, body temperature immediately after and muscle temperature 35 min after stunning were measured, as well as lean meat percentage and carcass weight.Results
TB pigs showed a lower cortisol response to the transport-induced stress than C pigs and also had a lower serum cortisol concentration after stunning. HSP70 content in the small intestine was higher in the TB pigs than in C pigs. TB pigs had a considerably lower carcass weight therefore produced a lower total amount of lean meat per carcass than C pigs.Conclusions
This study suggests that prolonged or repeated stress in the form of tail biting causes a blunted stress response, possibly a sign of hypocortisolism. In addition, it underlines the importance of reducing tail biting, both from an animal welfare and an economic point-of-view. 相似文献48.
G. Kubin 《Zoonoses and public health》1967,14(6):543-552
49.
Estévez M Kylli P Puolanne E Kivikari R Heinonen M 《Journal of agricultural and food chemistry》2008,56(22):10933-10940
The effect of selected phenolic compounds, namely, gallic acid, cyanidin-3-glucoside, (+)-epicatechin, chlorogenic acid, genistein and rutin (50 and 200 microM), and alpha-tocopherol (50 microM) against the oxidation of oil-in-water emulsions (37 degrees C/10 days) containing 1% myofibrillar proteins (MPs), was investigated. Emulsions containing 1% bovine serum albumin (BSA) were also prepared for comparative purposes. Protein oxidation was assessed by measuring the loss of natural tryptophan fluorescence and the protein carbonyl gain by using fluorescence spectroscopy. Lipid oxidation was concurrently analyzed by measuring the increase of conjugated dienes (CDs) and hexanal. Proteins inhibited lipid oxidation in oil-in-water emulsions, and MPs showed a more intense antioxidant activity than BSA. MPs were also more resistant to oxidative deterioration than BSA. The different antioxidant capacity of MPs and BSA and their susceptibility to suffer oxidative reactions might be derived from their different amino acid composition and three-dimensional structures. The addition of the phenolic compounds resulted in a variety of effects, including both antioxidant and pro-oxidant effects. Gallic acid, cyanidin-3-glucoside, and genistein were the most efficient inhibitors of lipid and protein oxidation. The chemical structure of the phenolic compounds as well as the nature and conformation of the proteins were greatly influential on the overall effect against oxidative reactions. 相似文献
50.
Common objectives of afforestation of cut-away peatlands are the diminution of nutrition loads and the production of energy wood in an efficient and economic way. We studied the effect of fertilization and afforestation methods on the early establishment of downy birch (Betula pubescens Ehrh.) seedlings on a cut-away peatland. Six treatments of peat-ash, wood-ash, biotite, or PK-fertilizer were replicated in three blocks in different mixtures corresponding to 50 kg/ha of phosphorous. Birch seeds were sown in randomized halves of split plots, while other halves were naturally afforested. Natural afforestation was equal to sowing in terms of seedling amounts due to closeness of surrounding birch stands with abundant seed crops. After the first growing season the greatest quantities and dominant heights of birch seedlings appeared on the ash-fertilized plots, whereas on the unfertilized areas both the establishment and growth of seedlings was very poor. On the other hand, the quantity of Scots pine (Pinus sylvestris L.) seedlings was more than three times higher on the unfertilized areas compared to the ash-fertilized areas. The differences between the fertilized and the unfertilized areas accentuated during the four observation years. Our results support regular use of ash-fertilizers for the afforestation of cut-away peatlands instead of the ash being deposited as a waste in landfills. 相似文献